2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1074
    Warangalone
    		Inhibitor
    Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50 of 3.5 μM.
    Warangalone
  • HY-16973S
    Fluralaner-13C2,15N,d3
    		Inhibitor 98.35%
    Fluralaner-13C2,15N,d3 is the deuterium, 13C-, and 15-labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels.
    Fluralaner-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N,d<sub>3</sub>
  • HY-135286A
    (+)-Neomenthol
    		Inhibitor
    (+)-Neomenthol is a potent miticide. (+)-Neomenthol shows acaricidal activitie with LD50 values of 0.32, 0.256 µg/mL for Dermatophagoides farinae and Dermatophagoides pteronyssinus, respectively.
    (+)-Neomenthol
  • HY-W078844
    PfDHODH-IN-2
    		Inhibitor 99.83%
    PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.
    PfDHODH-IN-2
  • HY-121211
    Digitolutein
    		Inhibitor
    Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection.
    Digitolutein
  • HY-123305
    5-Hydroxymebendazole
    		99.92%
    5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals.
    5-Hydroxymebendazole
  • HY-B0806S
    Proguanil-d6
    		Inhibitor 99.31%
    Proguanil-d6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial agent.
    Proguanil-d<sub>6</sub>
  • HY-128468
    1,2-Dimyristoyl-sn-glycerol
    		99.96%
    1,2-Dimyristoyl-sn-glycerol is a saturated diacylglycerol and a weak second messenger for the activation of PKC.
    1,2-Dimyristoyl-sn-glycerol
  • HY-B0945
    Nitromide
    		Inhibitor 98.19%
    Nitromide is an anti-parasitic agent.
    Nitromide
  • HY-B0497R
    Niclosamide (Standard)
    		Inhibitor
    Niclosamide (Standard) is the analytical standard of Niclosamide. This product is intended for research and analytical applications. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research. Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells.
    Niclosamide (Standard)
  • HY-W020111
    7-Chloro-4-(piperazin-1-yl)quinoline
    		Inhibitor 98.63%
    7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively.
    7-Chloro-4-(piperazin-1-yl)quinoline
  • HY-B1120
    Temephos
    		Inhibitor 99.01%
    Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae.
    Temephos
  • HY-B1004
    Dinitolmide
    		Inhibitor 99.66%
    Dinitolmide (Zoalene), a fodder additive for poultry, has anti-coccidial effect. Dinitolmide can be used to prevent infections induced by Eimeria, such as Eimeria tenella, Eimeria necatrix, Eimeria brunette, and so on.
    Dinitolmide
  • HY-W111370
    2-Nitroamino-2-imidazoline
    		Inhibitor
    2-Nitroamino-2-imidazoline is an intermediate in the synthesis of the neonicotinoid insecticide Imidacloprid (HY-B0838).
    2-Nitroamino-2-imidazoline
  • HY-155655
    JC-229
    		Inhibitor
    JC-229 is a TbRPA1 inhibitor. JC-229 targets RPA1 in Trypanosoma brucei. JC-229 can be used for the research of Human African Trypanosomiasis (HAT).
    JC-229
  • HY-B1186
    Dixanthogen
    		Inhibitor ≥98.0%
    Dixanthogen is an ectoparasiticide.
    Dixanthogen
  • HY-B0621R
    Triclabendazole (Standard)
    		Inhibitor
    Triclabendazole (Standard) is the analytical standard of Triclabendazole. This product is intended for research and analytical applications. Triclabendazole is an orally active parasite inhibitor. Triclabendazole has anti-Leishmania activity and induces gasdermin E (GSDME)-dependent pyroptosis by caspase-3 activation. Triclabendazole can be used for the research of fasciola hepatica.
    Triclabendazole (Standard)
  • HY-B2066
    Clofentezine
    		Inhibitor 98.35%
    Clofentezine is a growth inhibitor that is highly lethal to mites.
    Clofentezine
  • HY-101715
    Panidazole
    		Inhibitor 99.74%
    Panidazole is an amoebicide.
    Panidazole
  • HY-W588212
    trans-Permethrin
    		Inhibitor 99.88%
    trans-Permethrin is a transconfiguration of Permethrin (HY-B0887). Permethrin is an insecticide and neurotoxin.
    trans-Permethrin
Parasite Isoform Comparison

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